Salmonella osteomyelitis presenting as "hand-foot syndrome" in sickle-cell disease.

نویسنده

  • W J Noonan
چکیده

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Salmonella Osteomyelitis of the Hand in an Infant with Sickle Cell Disease

Salmonella osteomyelitis involving the hand is a rare, but potentially morbid, complication of sickle cell disease in children. This entity can be difficult to distinguish from the more frequent presentation of dactylitis, but accurate diagnosis is critical to direct proper treatment. We report on a 15-month-old patient with sickle cell disease who ultimately developed osteomyelitis of 1 hand a...

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Dactylitis: A Complication in Patients With Sickle Cell Disease

Sickle cell disease (SCD) is a group of disorders that affects hemoglobin, the red pigment in blood erythrocytes responsible for delivering oxygen throughout the body. This is the most commonly inherited blood disorder. One of the most widespread manifestations of SCD is painful vaso-occlusive crises and osteomyelitis. Dactylitis or hand-foot syndrome is the first clinical sign of SCD among chi...

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Sickle cell disease and related hemoglobinopathies.

Objectives 1. Describe different combinations of normal and abnormal hemoglobins and their phenotypic expression 2. Describe the pathophysiology of vasooclusion secondary to hemoglobinopathies 3. Define and describe hand-foot syndrome 4. Describe features of osteomyelitis secondary to sickle cell disease and its differentiation from bone infarct 5. Describe features of avascular necrosis of bon...

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Osteoarticular involvement in sickle cell disease

The osteoarticular involvement in sickle cell disease has been poorly studied and it is mainly characterized by osteonecrosis, osteomyelitis and arthritis. The most frequent complications and those that require hospital care in sickle cell disease patients are painful vaso-occlusive crises and osteomyelitis. The deoxygenation and polymerization of hemoglobin S, which results in sickling and vas...

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عنوان ژورنال:
  • British medical journal

دوره 284 6327  شماره 

صفحات  -

تاریخ انتشار 1982